Probably best know due to the successful Hollywood film, Apollo 13. While enroute to the moon, one of the oxygen tanks exploded leading to no oxygen and limited battery power for the command module. Despite multiple challenges, the crew was able to shelter in the lunar module and return safely to earth.

A few statistics:

• Crew: James A. Lovell Jr., Fred W. Haise Jr., John L. Swigert Jr.

• Launch Vehicle: Saturn V

• Date: April 11 -17, 1970